WG4: Transplantation, Inflammation and Immunity

WG4: Transplantation, Inflammation and Immunity

Transplantation, Inflammation and Immunity: evaluation of new/emerging transplantation techniques for AAK, dry eye disease, surgical outcomes, fibrosis, immune response, inflammation, and corneal neovascularization in aniridia-associated keratopathy.

Tasks:

• Analyse current best practices and success/failures of surgery in aniridia-associated keratopathy.
• Review best practices and evidence for keratoprosthesis use in aniridia.
• Identify treatment opportunities for improving the ocular surface prior to transplantation.
• Identify possible immune modulation approaches.

Deliverables:

• Manuscript describing success/failures of surgical treatments for aniridia-associated keratopathy across centres.
• Manuscript describing keratoprosthesis use and outcomes in aniridia, with special reference to intraocular pressure measurement.
• Consensus statement of new approaches to improve the ocular surface condition based on preclinical/clinical results.

WG 4 Leader: Dr Davide BORRONI (wg4@aniridia-net.eu)